Say\u0131 b\u00fcy\u00fcd\u00fck\u00e7e risk azal\u0131r.<\/p><\/blockquote>\n
T\u00fcm tarama testi sonu\u00e7lar\u0131 “…’de bir” (\u00f6rn. “100’de bir” veya “1500’de bir”) \u015feklinde verilir. Ayn\u0131 sonu\u00e7lar, y\u00fczdelik de\u011ferler olarak da verilebilir. Bu say\u0131lar, bebekte Down sendromu bulunma olas\u0131l\u0131\u011f\u0131n\u0131 g\u00f6sterir. \u00d6rne\u011fin, “100’de bir” sonucu, bebe\u011fin 100’de bir olas\u0131l\u0131kla Down sendromlu olaca\u011f\u0131 anlam\u0131na gelmektedir. “1500’de bir” sonucu, bebe\u011fin 1500’de bir olas\u0131l\u0131kla bu hastal\u0131\u011fa sahip olaca\u011f\u0131 anlam\u0131na gelmektedir.<\/p>\n
Tarama testinde y\u00fcksek risk bulunursa, doktorunuz bu konuda gerekli bilgi ve deste\u011fi size sa\u011flayacakt\u0131r. Bir sonraki a\u015famada ne yapaca\u011f\u0131n\u0131za karar vermek i\u00e7in yeterli zamana da sahip olacaks\u0131n\u0131z.<\/p>\n
Bu durumla kar\u015f\u0131 kar\u015f\u0131ya kalman\u0131z durumunda, \u00e7ok zor bir karar vermek zorunda oldu\u011funuzu bilmeniz gerekir. \u0130ki se\u00e7ene\u011finiz vard\u0131r. Bir tan\u0131 testi yapt\u0131rmamay\u0131 se\u00e7ebilirsiniz. Bu durumda, hamileli\u011finizin kalan b\u00f6l\u00fcm\u00fcn\u00fc tarama testi sonu\u00e7lar\u0131n\u0131 bilerek ge\u00e7irirsiniz ve bu \u00e7ok stresli olabilir.<\/p>\n
Di\u011fer se\u00e7enek tan\u0131 testini yapt\u0131rmakt\u0131r. Ancak bu durumun d\u00fc\u015f\u00fck tehlikesini biraz art\u0131rd\u0131\u011f\u0131n\u0131 g\u00f6z \u00f6n\u00fcnde bulundurman\u0131z gerekir.<\/p>\n
B\u00f6yle bir durumda, ne yapaca\u011f\u0131n\u0131 dikkatli \u015fekilde d\u00fc\u015f\u00fcnmeniz gerekir. Tarama testi sonucunu \u00f6\u011frendikten sonra zaman\u0131 geriye alamazs\u0131n\u0131z.<\/p>\n
Tarama testi sonu\u00e7lar\u0131,\u00a0tan\u0131 testi yapt\u0131rma konusundaki karar\u0131n\u0131z\u0131 nas\u0131l etkiler?<\/address>\n![\"Tarama](\"http:\/\/izmirkarsiyakakadindogummerkezi.com\/wp-content\/uploads\/2013\/02\/karar.jpg\")
Tarama testi algoritmas\u0131<\/p><\/div>\n
Tarama testi sonucunda bulunan risk oran\u0131na g\u00f6re nas\u0131l bira karar verilmesi gerekti\u011fi yandaki \u015fekilde \u00f6zetlenmi\u015ftir.<\/p>\n
Tan\u0131\u00a0testi \u00f6nerilmeyen kad\u0131nlar.<\/h4>\nDown Sendromlu bebeklerin %10’una tarama testleri ile tan\u0131 konamaz.<\/p><\/blockquote>\n
Tarama testi sonu\u00e7lar\u0131na g\u00f6re, bebe\u011finizde Down sendromu olma olas\u0131l\u0131\u011f\u0131n\u0131\u00a0d\u00fc\u015f\u00fck\u00a0ise tan\u0131 testi yapt\u0131rmay\u0131 d\u00fc\u015f\u00fcnmeyebilirsiniz.. Tarama testi sonu\u00e7lar\u0131n\u0131n b\u00fcy\u00fck b\u00f6l\u00fcm\u00fc (yakla\u015f\u0131k % 95), bu kategoride yer al\u0131r. Bu, d\u00fc\u015f\u00fck risk sonucu almak olarak bilinir.<\/p>\n
D\u00fc\u015f\u00fck risk sonucunun tam olarak ne anlama geldi\u011finin anla\u015f\u0131lmas\u0131 \u00f6nemlidir. Bu, bebe\u011finizin kesinlikle Down sendromu olma riski ta\u015f\u0131mad\u0131\u011f\u0131 anlam\u0131na gelmez. Yaln\u0131zca bu olas\u0131l\u0131\u011f\u0131n\u00a0d\u00fc\u015f\u00fck oldu\u011funu g\u00f6stermektedir. Bu sonuca g\u00f6re, \u00f6l\u00e7\u00fclen risk olas\u0131l\u0131\u011f\u0131,\u00a0di\u011fer bebeklerden\u00a0d\u00fc\u015f\u00fckt\u00fcr.<\/p>\n
Baz\u0131 bebeklerde Down sendromu tarama testleriyle tespit edilemedi\u011finden hala k\u00fc\u00e7\u00fck bir risk vard\u0131r. Bu durumun tarama testleriyle tespit edilememesinin nedeni, do\u011fal farkl\u0131l\u0131klar sebebiyle beklenen \u015fablonun kan testinde veya tarama \u00f6l\u00e7\u00fcmlerinde g\u00f6r\u00fclmemi\u015f olmas\u0131d\u0131r. Toplamda, Down sendromlu bebeklerin\u00a0y\u00fczde onu\u00a0tarama testleriyle tespit edilemez.<\/p>\n
Tan\u0131\u00a0testi \u00f6nerilen kad\u0131nlar.<\/h4>\n
Tarama testi sonu\u00e7lar\u0131na g\u00f6re, bebe\u011finizde Down sendromu olma olas\u0131l\u0131\u011f\u0131 y\u00fcksek ise, tan\u0131 testi yapt\u0131rman\u0131z uygun olur.\u00a0Tan\u0131 testi yapt\u0131rman\u0131z\u0131 gerektirecek\u00a0tarama testi sonu\u00e7lar\u0131, y\u00fcksek riskli sonu\u00e7lar olarak bilinir.<\/p>\n
Toplamda, tarama yap\u0131lan 30\u00a0anne aday\u0131ndan\u00a0birinde (% 3) “y\u00fcksek risk”\u00a0bulunur ve tan\u0131 testi yapt\u0131rmalar\u0131 \u00f6nerilir.<\/p>\n
Tarama testinden y\u00fcksek risk sonucu al\u0131nmas\u0131 durumunda, size daha fazla test yapt\u0131rman\u0131z uygun olur. Bu, bebekte kesin olarak Down sendromu bulundu\u011fu anlam\u0131na gelmez.<\/p>\n
Daha sonra\u00a0okuyaca\u011f\u0131n\u0131z \u00fczere,\u00a0tan\u0131 test yapt\u0131ran \u00e7o\u011fu\u00a0anne aday\u0131n\u0131n\u00a0bebe\u011finde Down sendromu olmad\u0131\u011f\u0131 g\u00f6r\u00fcl\u00fcr.<\/p>\n
Amniosentez ve koryonik villus \u00f6rne\u011fi incelemesi gibi, d\u00fc\u015f\u00fck riski olan y\u00f6ntemlere ba\u015fvurma gereksinimi nas\u0131l azalt\u0131labilir?<\/p>\n
Gebeli\u011fin 2. d\u00f6neminde (15. – 22. haftalar aras\u0131nda) yap\u0131lan amniosentez ve 1. d\u00f6neminde (10.-13. haftalar aras\u0131nda) yap\u0131lan koryonik villus \u00f6rne\u011fi incelemesi gibi, bir m\u00fcdahale ile \u00f6rnek al\u0131nmas\u0131 i\u015flemlerine invaziv y\u00f6ntem denilmektedir. ABD’de her y\u0131l 250.000 \u00fczerinde amniosentez yap\u0131ld\u0131\u011f\u0131 ve bunun bedelinin 200 milyon USD civar\u0131nda oldu\u011fu belirtilmektedir. Ayr\u0131ca, bu i\u015flemler s\u0131ras\u0131nda her 200 i\u015flemde bir d\u00fc\u015f\u00fck oldu\u011fu, her y\u0131l 1000 civar\u0131nda fetusun (cenin) bu \u015fekilde kaybedildi\u011fi belirtilmektedir.<\/p>\n
Bir tarama y\u00f6ntemi, ne kadar fazla gereksiz pozitif sonu\u00e7 veriyorsa, yani yalanc\u0131 pozitiflik oran\u0131 ne kadar y\u00fcksekse, o oranda da fazla amniosentez gere\u011fi ortaya \u00e7\u0131kacakt\u0131r. Bu nedenle, bir y\u00f6ntemin gereksiz amniosentez riskini azaltmas\u0131 i\u00e7in, yalanc\u0131 pozitiflik oran\u0131n\u0131n d\u00fc\u015f\u00fck olmas\u0131 gerekir. Bu nedenle, kabul edilebilir yalanc\u0131 pozitiflik oran\u0131 genelde %5olarak belirlenmektedir. \u00d6rne\u011fin \u00dc\u00e7l\u00fc Test ile belirleme de\u011feri %5 yalanc\u0131 pozitiflikle %69’dur. Ayn\u0131 sonu\u00e7, yani %69 belirleme de\u011feri, D\u00f6rtl\u00fc Test ile %3 yalanc\u0131 pozitiflikle elde edilmektedir. Yani hem \u00dc\u00e7l\u00fc, hem de D\u00f6rtl\u00fc Test ile her 100 Down Sendromlu gebelikten, tarama sonucu 69’u yakalanabilmektedir. Ancak bunlardan \u00dc\u00e7l\u00fc Test ile 5’i yalanc\u0131 pozitif olarak sonu\u00e7lan\u0131rken, D\u00f6rtl\u00fc Test ile 3’\u00fc yalanc\u0131 pozitif olarak sonu\u00e7lanmaktad\u0131r.<\/p>\n
Bir ba\u015fka deyi\u015fle, \u00fc\u00e7l\u00fc tarama testi kullan\u0131ld\u0131\u011f\u0131nda 100.000 ki\u015filik gebenin taranmas\u0131yla 111 ger\u00e7ek Down olgusundan 76’s\u0131 (%69) yakalan\u0131r iken, 5.000 pozitif olgu (% 5 yalanc\u0131 pozitiflikle) ortaya \u00e7\u0131kmakta, bunun tamam\u0131 amniosenteze gitmektedir. D\u00f6rtl\u00fc Test ile ise ayn\u0131 toplulukta, 111 ger\u00e7ek Down olgusundan 76’s\u0131n\u0131 (%69) yakalamak i\u00e7in, 3.000 pozitif Down testi (% 3 yalanc\u0131 pozitiflik) sonucu al\u0131nmakta, amniosenteze gidecek olgu say\u0131s\u0131 5.000’den 3.000’e inmektedir.<\/p>\n
Integre Test ile ise amniosenteze gidecek gebe say\u0131s\u0131 \u00fc\u00e7l\u00fc testin 15’te biri, yani 5000 gebe yerine yaln\u0131zca 330 gebe olacakt\u0131r. Bu farkl\u0131l\u0131klar da hem gereksiz amniosentez ve d\u00fc\u015f\u00fck olas\u0131l\u0131\u011f\u0131n\u0131 azaltacak, hem de fazladan maddi kay\u0131plar\u0131 azaltacakt\u0131r.
\nBu nedenle, tarama y\u00f6ntemlerinin yalanc\u0131 pozitiflik oranlar\u0131 d\u00fc\u015f\u00fcr\u00fclerek, gereksiz amniosentez i\u015flemleri azalt\u0131lmaya \u00e7al\u0131\u015f\u0131lmaktad\u0131r<\/p>\n
Farkl\u0131 Laboratuvarlar\u0131n Sonu\u00e7lar\u0131<\/h4>\n
Bu durum m\u00fcmk\u00fcnd\u00fcr. Bu durumu etkileyen \u00e7e\u015fitli fakt\u00f6rler vard\u0131r. \u015e\u00f6yle ki:
\na.) Farkl\u0131 toplumlar\u0131n median (ortalama) de\u011ferleri farkl\u0131d\u0131r. Bu de\u011ferler kullan\u0131lan kit, y\u00f6ntem ve laboratuvar ko\u015fullar\u0131na g\u00f6re de de\u011fi\u015fiklik g\u00f6sterir. Laboratuvar, kendi toplumu ve hastalar\u0131na y\u00f6nelik kendi \u00f6zg\u00fcn median de\u011ferlerini olu\u015fturmal\u0131d\u0131r. E\u011fer ba\u015fka kaynaklar\u0131n median de\u011ferleri kullan\u0131l\u0131rsa, hatal\u0131 sonu\u00e7lar al\u0131nacakt\u0131r.
\nb.) Risk s\u0131n\u0131r\u0131 (Risk cut-off) belirlemesi \u00e7ok \u00f6nemlidir. Bu s\u0131n\u0131r, 1\/250 veya 1\/380 olarak belirlenmektedir. \u0130ki laboratuvar, hastan\u0131n riskini \u00f6rne\u011fin 1\/270 olarak ayn\u0131 de\u011ferde bulsa bile, sonu\u00e7 birinde pozitif, di\u011ferinde ise negatif olarak verilecektir. Sonu\u00e7, s\u0131n\u0131r de\u011ferin 1\/250 oldu\u011fu laboratuvar taraf\u0131ndan negatif, 1\/380 oldu\u011fu laboratuvar taraf\u0131ndan da pozitif olarak verilecektir.
\nS\u0131n\u0131r de\u011feri 1\/380 olarak belirlemek daha fazla pozitif sonu\u00e7, ancak ayn\u0131 zamanda daha y\u00fcksek oranda da yalanc\u0131 pozitiflik anlam\u0131na gelmektedir. Bu nedenle, T\u00fcrkiye i\u00e7in 1\/250 s\u0131n\u0131r de\u011fer daha ger\u00e7ek\u00e7idir. B\u00f6ylelikle yalanc\u0131 pozitiflik daha az ve amniosenteze giden olgu say\u0131s\u0131 da daha az olacakt\u0131r.<\/p>\n
Risk De\u011ferlendirmesi<\/h4>\n1980-90’l\u0131 y\u0131llardan beri tarama testi sonu\u00e7lar\u0131na g\u00f6re 1\/250 riski s\u0131n\u0131r kabul edilir ve 1\/250’nin \u00fczerindeki riskler y\u00fcksek, alt\u0131ndakiler d\u00fc\u015f\u00fck olarak de\u011ferlendirlir. Bu s\u0131n\u0131r de\u011feri, amniyosentez sonras\u0131nda g\u00f6r\u00fclen komplikasyon oran\u0131na g\u00f6re belirlenmi\u015ftir. Sonu\u00e7 olarak bebekte Down Sendromu g\u00f6r\u00fclme riski 1\/250’den daha d\u00fc\u015f\u00fck ise amniyosentez daha risklidir. Dolay\u0131s\u0131yla amniyosentez \u00f6nerilmez. Di\u011fer taraftan risk s\u0131n\u0131r de\u011fere g\u00f6re daha y\u00fcksek ise amniyosentezin riski daha d\u00fc\u015f\u00fckt\u00fcr ve yap\u0131lmal\u0131d\u0131r.<\/div>\nBirka\u00e7 y\u0131l \u00f6nce Amerikan Kad\u0131n Hastal\u0131klar\u0131 ve Do\u011fum Hekimleri Koleji (ACOG) d\u00fc\u015f\u00fck veya y\u00fcksek risk belirtilmesi yerine say\u0131sal risk anlat\u0131lmas\u0131 gerekti\u011fine karar verdi.<\/div>\nAnne ya\u015f\u0131n\u0131 temel alarak laboratuvar sonu\u00e7lar\u0131na g\u00f6re hesaplanan Down Sendromu riski fetal ya\u015f da kullan\u0131larak tekrar de\u011ferlendirilir. Anne ya\u015f\u0131 ilerledik\u00e7e bebekte Down Sendromu g\u00f6r\u00fclme riskinin de artt\u0131\u011f\u0131n\u0131 biliyoruz.<\/div>\n\u00d6rne\u011fin t\u00fcm test sonu\u00e7lar\u0131n\u0131n 1 MoM (yani tam normal) \u00e7\u0131kt\u0131\u011f\u0131n\u0131 varsayal\u0131m, Down Sendromu riski d\u00f6rtte bir daha d\u00fc\u015f\u00fck bulunacakt\u0131r. Bu, klinik \u00e7al\u0131\u015fmalara g\u00f6re hesaplanm\u0131\u015f bir orand\u0131r. \u00d6rne\u011fin 25 ya\u015f\u0131nda bir kad\u0131n\u0131n tarama testi yapmaks\u0131z\u0131n Down Sendromu riski 1\/1100’d\u00fcr. Az \u00f6nceki sonu\u00e7lar\u0131n al\u0131nd\u0131\u011f\u0131 varsay\u0131l\u0131rsa Down Sendromu riski 1\/4400 olarak hesaplan\u0131r. 35 ya\u015f\u0131nda bir kad\u0131nda test yap\u0131lmaks\u0131z\u0131n Down Sendromlu bebek do\u011furma riski 1\/250 iken az \u00f6nceki test sonu\u00e7lar\u0131 al\u0131n\u0131rsa risk 1\/1000 olarak hesaplan\u0131r. Ayn\u0131 anne aday\u0131 45 ya\u015f\u0131nda oldu\u011funda test \u00f6ncesi risk 1\/20 iken test sonucuna g\u00f6re 1\/80 olarak bulunur.<\/div>\n\u015eimdi ba\u015fka bir test sonucu inceleyelim. Bu test sonucu da Down Sendromu riskini 4 kat art\u0131rs\u0131n. Bu durumda 25 ya\u015f\u0131nda anne aday\u0131n\u0131n riski 1\/275, 35 ya\u015f\u0131ndaki 1\/62 ve 45 ya\u015f\u0131ndaki 1\/5 olarak hesaplan\u0131r.<\/div>\nBuradan da anla\u015f\u0131l\u0131yor ki anne aday\u0131n\u0131n ya\u015f\u0131 halen en Down Sendromu riski hesaplamak i\u00e7in \u00e7ok \u00f6nemlidir. Down Sendromu riski 35 ya\u015f\u0131ndaki bir kad\u0131nda 1\/250, yan\u0131 amniyosentez i\u00e7in s\u0131n\u0131r kabul edilen orand\u0131r. Eskiden 35 ya\u015f \u00fcst\u00fc i\u00e7in tarama testi yap\u0131lmas\u0131 \u00f6nerilirken 2007 y\u0131l\u0131nda ACOG yeni bir a\u00e7\u0131klama ile t\u00fcm anne adaylar\u0131n\u0131n tarama testinden yararlanmas\u0131n\u0131 \u00f6nerdi.<\/div>\n","protected":false},"excerpt":{"rendered":"Bir tarama testi bana hangi bilgileri verir? Say\u0131 b\u00fcy\u00fcd\u00fck\u00e7e risk azal\u0131r. T\u00fcm tarama testi sonu\u00e7lar\u0131 “…’de bir” (\u00f6rn. “100’de bir” veya “1500’de bir”) \u015feklinde verilir. Ayn\u0131 sonu\u00e7lar, y\u00fczdelik de\u011ferler olarak da verilebilir. Bu say\u0131lar, bebekte Down sendromu bulunma olas\u0131l\u0131\u011f\u0131n\u0131 g\u00f6sterir. \u00d6rne\u011fin, “100’de bir” sonucu, bebe\u011fin 100’de bir olas\u0131l\u0131kla Down sendromlu olaca\u011f\u0131 anlam\u0131na gelmektedir. “1500’de bir” […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[33],"tags":[],"yoast_head":"\n
Down Sendromu Tarama Testi Sonu\u00e7lar\u0131 - \u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Down Sendromu Tarama Testi Sonu\u00e7lar\u0131 - \u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi\" \/>\n<meta property=\"og:description\" content=\"Bir tarama testi bana hangi bilgileri verir? Say\u0131 b\u00fcy\u00fcd\u00fck\u00e7e risk azal\u0131r. T\u00fcm tarama testi sonu\u00e7lar\u0131 “…’de bir” (\u00f6rn. “100’de bir” veya “1500’de bir”) \u015feklinde verilir. Ayn\u0131 sonu\u00e7lar, y\u00fczdelik de\u011ferler olarak da verilebilir. Bu say\u0131lar, bebekte Down sendromu bulunma olas\u0131l\u0131\u011f\u0131n\u0131 g\u00f6sterir. \u00d6rne\u011fin, “100’de bir” sonucu, bebe\u011fin 100’de bir olas\u0131l\u0131kla Down sendromlu olaca\u011f\u0131 anlam\u0131na gelmektedir. “1500’de bir” […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/\" \/>\n<meta property=\"og:site_name\" content=\"\u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi\" \/>\n<meta property=\"article:publisher\" content=\"http:\/\/facebook.com\/op.dr.hakankilavuz\" \/>\n<meta property=\"article:published_time\" content=\"2013-02-16T20:47:16+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/izmirkarsiyakakadindogummerkezi.com\/wp-content\/uploads\/2013\/02\/karar.jpg\" \/>\n<meta name=\"author\" content=\"hakan\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@opdrkilavuz\" \/>\n<meta name=\"twitter:site\" content=\"@opdrkilavuz\" \/>\n<meta name=\"twitter:label1\" content=\"Yazan:\" \/>\n\t<meta name=\"twitter:data1\" content=\"hakan\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tahmini okuma s\u00fcresi\" \/>\n\t<meta name=\"twitter:data2\" content=\"8 dakika\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/\",\"url\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/\",\"name\":\"Down Sendromu Tarama Testi Sonu\u00e7lar\u0131 - \u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi\",\"isPartOf\":{\"@id\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/#website\"},\"datePublished\":\"2013-02-16T20:47:16+00:00\",\"dateModified\":\"2013-02-16T20:47:16+00:00\",\"author\":{\"@id\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/#\/schema\/person\/8a752617726b9b02bd10a28c1c4509a4\"},\"breadcrumb\":{\"@id\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/#breadcrumb\"},\"inLanguage\":\"tr\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Ana sayfa\",\"item\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Down Sendromu Tarama Testi Sonu\u00e7lar\u0131\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/#website\",\"url\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/\",\"name\":\"\u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi\",\"description\":\"Op. 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Say\u0131 b\u00fcy\u00fcd\u00fck\u00e7e risk azal\u0131r. T\u00fcm tarama testi sonu\u00e7lar\u0131 “…’de bir” (\u00f6rn. “100’de bir” veya “1500’de bir”) \u015feklinde verilir. Ayn\u0131 sonu\u00e7lar, y\u00fczdelik de\u011ferler olarak da verilebilir. Bu say\u0131lar, bebekte Down sendromu bulunma olas\u0131l\u0131\u011f\u0131n\u0131 g\u00f6sterir. \u00d6rne\u011fin, “100’de bir” sonucu, bebe\u011fin 100’de bir olas\u0131l\u0131kla Down sendromlu olaca\u011f\u0131 anlam\u0131na gelmektedir. “1500’de bir” […]","og_url":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/","og_site_name":"\u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi","article_publisher":"http:\/\/facebook.com\/op.dr.hakankilavuz","article_published_time":"2013-02-16T20:47:16+00:00","og_image":[{"url":"http:\/\/izmirkarsiyakakadindogummerkezi.com\/wp-content\/uploads\/2013\/02\/karar.jpg"}],"author":"hakan","twitter_card":"summary_large_image","twitter_creator":"@opdrkilavuz","twitter_site":"@opdrkilavuz","twitter_misc":{"Yazan:":"hakan","Tahmini okuma s\u00fcresi":"8 dakika"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/","url":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/","name":"Down Sendromu Tarama Testi Sonu\u00e7lar\u0131 - \u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi","isPartOf":{"@id":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/#website"},"datePublished":"2013-02-16T20:47:16+00:00","dateModified":"2013-02-16T20:47:16+00:00","author":{"@id":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/#\/schema\/person\/8a752617726b9b02bd10a28c1c4509a4"},"breadcrumb":{"@id":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/#breadcrumb"},"inLanguage":"tr","potentialAction":[{"@type":"ReadAction","target":["https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Ana sayfa","item":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/"},{"@type":"ListItem","position":2,"name":"Down Sendromu Tarama Testi Sonu\u00e7lar\u0131"}]},{"@type":"WebSite","@id":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/#website","url":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/","name":"\u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi","description":"Op. 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Down Sendromlu bebeklerin %10’una tarama testleri ile tan\u0131 konamaz.<\/p><\/blockquote>\n
Tarama testi sonu\u00e7lar\u0131na g\u00f6re, bebe\u011finizde Down sendromu olma olas\u0131l\u0131\u011f\u0131n\u0131\u00a0d\u00fc\u015f\u00fck\u00a0ise tan\u0131 testi yapt\u0131rmay\u0131 d\u00fc\u015f\u00fcnmeyebilirsiniz.. Tarama testi sonu\u00e7lar\u0131n\u0131n b\u00fcy\u00fck b\u00f6l\u00fcm\u00fc (yakla\u015f\u0131k % 95), bu kategoride yer al\u0131r. Bu, d\u00fc\u015f\u00fck risk sonucu almak olarak bilinir.<\/p>\n
D\u00fc\u015f\u00fck risk sonucunun tam olarak ne anlama geldi\u011finin anla\u015f\u0131lmas\u0131 \u00f6nemlidir. Bu, bebe\u011finizin kesinlikle Down sendromu olma riski ta\u015f\u0131mad\u0131\u011f\u0131 anlam\u0131na gelmez. Yaln\u0131zca bu olas\u0131l\u0131\u011f\u0131n\u00a0d\u00fc\u015f\u00fck oldu\u011funu g\u00f6stermektedir. Bu sonuca g\u00f6re, \u00f6l\u00e7\u00fclen risk olas\u0131l\u0131\u011f\u0131,\u00a0di\u011fer bebeklerden\u00a0d\u00fc\u015f\u00fckt\u00fcr.<\/p>\n
Baz\u0131 bebeklerde Down sendromu tarama testleriyle tespit edilemedi\u011finden hala k\u00fc\u00e7\u00fck bir risk vard\u0131r. Bu durumun tarama testleriyle tespit edilememesinin nedeni, do\u011fal farkl\u0131l\u0131klar sebebiyle beklenen \u015fablonun kan testinde veya tarama \u00f6l\u00e7\u00fcmlerinde g\u00f6r\u00fclmemi\u015f olmas\u0131d\u0131r. Toplamda, Down sendromlu bebeklerin\u00a0y\u00fczde onu\u00a0tarama testleriyle tespit edilemez.<\/p>\n
Tan\u0131\u00a0testi \u00f6nerilen kad\u0131nlar.<\/h4>\n
Tarama testi sonu\u00e7lar\u0131na g\u00f6re, bebe\u011finizde Down sendromu olma olas\u0131l\u0131\u011f\u0131 y\u00fcksek ise, tan\u0131 testi yapt\u0131rman\u0131z uygun olur.\u00a0Tan\u0131 testi yapt\u0131rman\u0131z\u0131 gerektirecek\u00a0tarama testi sonu\u00e7lar\u0131, y\u00fcksek riskli sonu\u00e7lar olarak bilinir.<\/p>\n
Toplamda, tarama yap\u0131lan 30\u00a0anne aday\u0131ndan\u00a0birinde (% 3) “y\u00fcksek risk”\u00a0bulunur ve tan\u0131 testi yapt\u0131rmalar\u0131 \u00f6nerilir.<\/p>\n
Tarama testinden y\u00fcksek risk sonucu al\u0131nmas\u0131 durumunda, size daha fazla test yapt\u0131rman\u0131z uygun olur. Bu, bebekte kesin olarak Down sendromu bulundu\u011fu anlam\u0131na gelmez.<\/p>\n
Daha sonra\u00a0okuyaca\u011f\u0131n\u0131z \u00fczere,\u00a0tan\u0131 test yapt\u0131ran \u00e7o\u011fu\u00a0anne aday\u0131n\u0131n\u00a0bebe\u011finde Down sendromu olmad\u0131\u011f\u0131 g\u00f6r\u00fcl\u00fcr.<\/p>\n
Amniosentez ve koryonik villus \u00f6rne\u011fi incelemesi gibi, d\u00fc\u015f\u00fck riski olan y\u00f6ntemlere ba\u015fvurma gereksinimi nas\u0131l azalt\u0131labilir?<\/p>\n
Gebeli\u011fin 2. d\u00f6neminde (15. – 22. haftalar aras\u0131nda) yap\u0131lan amniosentez ve 1. d\u00f6neminde (10.-13. haftalar aras\u0131nda) yap\u0131lan koryonik villus \u00f6rne\u011fi incelemesi gibi, bir m\u00fcdahale ile \u00f6rnek al\u0131nmas\u0131 i\u015flemlerine invaziv y\u00f6ntem denilmektedir. ABD’de her y\u0131l 250.000 \u00fczerinde amniosentez yap\u0131ld\u0131\u011f\u0131 ve bunun bedelinin 200 milyon USD civar\u0131nda oldu\u011fu belirtilmektedir. Ayr\u0131ca, bu i\u015flemler s\u0131ras\u0131nda her 200 i\u015flemde bir d\u00fc\u015f\u00fck oldu\u011fu, her y\u0131l 1000 civar\u0131nda fetusun (cenin) bu \u015fekilde kaybedildi\u011fi belirtilmektedir.<\/p>\n
Bir tarama y\u00f6ntemi, ne kadar fazla gereksiz pozitif sonu\u00e7 veriyorsa, yani yalanc\u0131 pozitiflik oran\u0131 ne kadar y\u00fcksekse, o oranda da fazla amniosentez gere\u011fi ortaya \u00e7\u0131kacakt\u0131r. Bu nedenle, bir y\u00f6ntemin gereksiz amniosentez riskini azaltmas\u0131 i\u00e7in, yalanc\u0131 pozitiflik oran\u0131n\u0131n d\u00fc\u015f\u00fck olmas\u0131 gerekir. Bu nedenle, kabul edilebilir yalanc\u0131 pozitiflik oran\u0131 genelde %5olarak belirlenmektedir. \u00d6rne\u011fin \u00dc\u00e7l\u00fc Test ile belirleme de\u011feri %5 yalanc\u0131 pozitiflikle %69’dur. Ayn\u0131 sonu\u00e7, yani %69 belirleme de\u011feri, D\u00f6rtl\u00fc Test ile %3 yalanc\u0131 pozitiflikle elde edilmektedir. Yani hem \u00dc\u00e7l\u00fc, hem de D\u00f6rtl\u00fc Test ile her 100 Down Sendromlu gebelikten, tarama sonucu 69’u yakalanabilmektedir. Ancak bunlardan \u00dc\u00e7l\u00fc Test ile 5’i yalanc\u0131 pozitif olarak sonu\u00e7lan\u0131rken, D\u00f6rtl\u00fc Test ile 3’\u00fc yalanc\u0131 pozitif olarak sonu\u00e7lanmaktad\u0131r.<\/p>\n
Bir ba\u015fka deyi\u015fle, \u00fc\u00e7l\u00fc tarama testi kullan\u0131ld\u0131\u011f\u0131nda 100.000 ki\u015filik gebenin taranmas\u0131yla 111 ger\u00e7ek Down olgusundan 76’s\u0131 (%69) yakalan\u0131r iken, 5.000 pozitif olgu (% 5 yalanc\u0131 pozitiflikle) ortaya \u00e7\u0131kmakta, bunun tamam\u0131 amniosenteze gitmektedir. D\u00f6rtl\u00fc Test ile ise ayn\u0131 toplulukta, 111 ger\u00e7ek Down olgusundan 76’s\u0131n\u0131 (%69) yakalamak i\u00e7in, 3.000 pozitif Down testi (% 3 yalanc\u0131 pozitiflik) sonucu al\u0131nmakta, amniosenteze gidecek olgu say\u0131s\u0131 5.000’den 3.000’e inmektedir.<\/p>\n
Integre Test ile ise amniosenteze gidecek gebe say\u0131s\u0131 \u00fc\u00e7l\u00fc testin 15’te biri, yani 5000 gebe yerine yaln\u0131zca 330 gebe olacakt\u0131r. Bu farkl\u0131l\u0131klar da hem gereksiz amniosentez ve d\u00fc\u015f\u00fck olas\u0131l\u0131\u011f\u0131n\u0131 azaltacak, hem de fazladan maddi kay\u0131plar\u0131 azaltacakt\u0131r.
\nBu nedenle, tarama y\u00f6ntemlerinin yalanc\u0131 pozitiflik oranlar\u0131 d\u00fc\u015f\u00fcr\u00fclerek, gereksiz amniosentez i\u015flemleri azalt\u0131lmaya \u00e7al\u0131\u015f\u0131lmaktad\u0131r<\/p>\n
Farkl\u0131 Laboratuvarlar\u0131n Sonu\u00e7lar\u0131<\/h4>\n
Bu durum m\u00fcmk\u00fcnd\u00fcr. Bu durumu etkileyen \u00e7e\u015fitli fakt\u00f6rler vard\u0131r. \u015e\u00f6yle ki:
\na.) Farkl\u0131 toplumlar\u0131n median (ortalama) de\u011ferleri farkl\u0131d\u0131r. Bu de\u011ferler kullan\u0131lan kit, y\u00f6ntem ve laboratuvar ko\u015fullar\u0131na g\u00f6re de de\u011fi\u015fiklik g\u00f6sterir. Laboratuvar, kendi toplumu ve hastalar\u0131na y\u00f6nelik kendi \u00f6zg\u00fcn median de\u011ferlerini olu\u015fturmal\u0131d\u0131r. E\u011fer ba\u015fka kaynaklar\u0131n median de\u011ferleri kullan\u0131l\u0131rsa, hatal\u0131 sonu\u00e7lar al\u0131nacakt\u0131r.
\nb.) Risk s\u0131n\u0131r\u0131 (Risk cut-off) belirlemesi \u00e7ok \u00f6nemlidir. Bu s\u0131n\u0131r, 1\/250 veya 1\/380 olarak belirlenmektedir. \u0130ki laboratuvar, hastan\u0131n riskini \u00f6rne\u011fin 1\/270 olarak ayn\u0131 de\u011ferde bulsa bile, sonu\u00e7 birinde pozitif, di\u011ferinde ise negatif olarak verilecektir. Sonu\u00e7, s\u0131n\u0131r de\u011ferin 1\/250 oldu\u011fu laboratuvar taraf\u0131ndan negatif, 1\/380 oldu\u011fu laboratuvar taraf\u0131ndan da pozitif olarak verilecektir.
\nS\u0131n\u0131r de\u011feri 1\/380 olarak belirlemek daha fazla pozitif sonu\u00e7, ancak ayn\u0131 zamanda daha y\u00fcksek oranda da yalanc\u0131 pozitiflik anlam\u0131na gelmektedir. Bu nedenle, T\u00fcrkiye i\u00e7in 1\/250 s\u0131n\u0131r de\u011fer daha ger\u00e7ek\u00e7idir. B\u00f6ylelikle yalanc\u0131 pozitiflik daha az ve amniosenteze giden olgu say\u0131s\u0131 da daha az olacakt\u0131r.<\/p>\n
Risk De\u011ferlendirmesi<\/h4>\n1980-90’l\u0131 y\u0131llardan beri tarama testi sonu\u00e7lar\u0131na g\u00f6re 1\/250 riski s\u0131n\u0131r kabul edilir ve 1\/250’nin \u00fczerindeki riskler y\u00fcksek, alt\u0131ndakiler d\u00fc\u015f\u00fck olarak de\u011ferlendirlir. Bu s\u0131n\u0131r de\u011feri, amniyosentez sonras\u0131nda g\u00f6r\u00fclen komplikasyon oran\u0131na g\u00f6re belirlenmi\u015ftir. Sonu\u00e7 olarak bebekte Down Sendromu g\u00f6r\u00fclme riski 1\/250’den daha d\u00fc\u015f\u00fck ise amniyosentez daha risklidir. Dolay\u0131s\u0131yla amniyosentez \u00f6nerilmez. Di\u011fer taraftan risk s\u0131n\u0131r de\u011fere g\u00f6re daha y\u00fcksek ise amniyosentezin riski daha d\u00fc\u015f\u00fckt\u00fcr ve yap\u0131lmal\u0131d\u0131r.<\/div>\nBirka\u00e7 y\u0131l \u00f6nce Amerikan Kad\u0131n Hastal\u0131klar\u0131 ve Do\u011fum Hekimleri Koleji (ACOG) d\u00fc\u015f\u00fck veya y\u00fcksek risk belirtilmesi yerine say\u0131sal risk anlat\u0131lmas\u0131 gerekti\u011fine karar verdi.<\/div>\nAnne ya\u015f\u0131n\u0131 temel alarak laboratuvar sonu\u00e7lar\u0131na g\u00f6re hesaplanan Down Sendromu riski fetal ya\u015f da kullan\u0131larak tekrar de\u011ferlendirilir. Anne ya\u015f\u0131 ilerledik\u00e7e bebekte Down Sendromu g\u00f6r\u00fclme riskinin de artt\u0131\u011f\u0131n\u0131 biliyoruz.<\/div>\n\u00d6rne\u011fin t\u00fcm test sonu\u00e7lar\u0131n\u0131n 1 MoM (yani tam normal) \u00e7\u0131kt\u0131\u011f\u0131n\u0131 varsayal\u0131m, Down Sendromu riski d\u00f6rtte bir daha d\u00fc\u015f\u00fck bulunacakt\u0131r. Bu, klinik \u00e7al\u0131\u015fmalara g\u00f6re hesaplanm\u0131\u015f bir orand\u0131r. \u00d6rne\u011fin 25 ya\u015f\u0131nda bir kad\u0131n\u0131n tarama testi yapmaks\u0131z\u0131n Down Sendromu riski 1\/1100’d\u00fcr. Az \u00f6nceki sonu\u00e7lar\u0131n al\u0131nd\u0131\u011f\u0131 varsay\u0131l\u0131rsa Down Sendromu riski 1\/4400 olarak hesaplan\u0131r. 35 ya\u015f\u0131nda bir kad\u0131nda test yap\u0131lmaks\u0131z\u0131n Down Sendromlu bebek do\u011furma riski 1\/250 iken az \u00f6nceki test sonu\u00e7lar\u0131 al\u0131n\u0131rsa risk 1\/1000 olarak hesaplan\u0131r. Ayn\u0131 anne aday\u0131 45 ya\u015f\u0131nda oldu\u011funda test \u00f6ncesi risk 1\/20 iken test sonucuna g\u00f6re 1\/80 olarak bulunur.<\/div>\n\u015eimdi ba\u015fka bir test sonucu inceleyelim. Bu test sonucu da Down Sendromu riskini 4 kat art\u0131rs\u0131n. Bu durumda 25 ya\u015f\u0131nda anne aday\u0131n\u0131n riski 1\/275, 35 ya\u015f\u0131ndaki 1\/62 ve 45 ya\u015f\u0131ndaki 1\/5 olarak hesaplan\u0131r.<\/div>\nBuradan da anla\u015f\u0131l\u0131yor ki anne aday\u0131n\u0131n ya\u015f\u0131 halen en Down Sendromu riski hesaplamak i\u00e7in \u00e7ok \u00f6nemlidir. Down Sendromu riski 35 ya\u015f\u0131ndaki bir kad\u0131nda 1\/250, yan\u0131 amniyosentez i\u00e7in s\u0131n\u0131r kabul edilen orand\u0131r. Eskiden 35 ya\u015f \u00fcst\u00fc i\u00e7in tarama testi yap\u0131lmas\u0131 \u00f6nerilirken 2007 y\u0131l\u0131nda ACOG yeni bir a\u00e7\u0131klama ile t\u00fcm anne adaylar\u0131n\u0131n tarama testinden yararlanmas\u0131n\u0131 \u00f6nerdi.<\/div>\n","protected":false},"excerpt":{"rendered":"Bir tarama testi bana hangi bilgileri verir? Say\u0131 b\u00fcy\u00fcd\u00fck\u00e7e risk azal\u0131r. T\u00fcm tarama testi sonu\u00e7lar\u0131 “…’de bir” (\u00f6rn. “100’de bir” veya “1500’de bir”) \u015feklinde verilir. Ayn\u0131 sonu\u00e7lar, y\u00fczdelik de\u011ferler olarak da verilebilir. Bu say\u0131lar, bebekte Down sendromu bulunma olas\u0131l\u0131\u011f\u0131n\u0131 g\u00f6sterir. \u00d6rne\u011fin, “100’de bir” sonucu, bebe\u011fin 100’de bir olas\u0131l\u0131kla Down sendromlu olaca\u011f\u0131 anlam\u0131na gelmektedir. “1500’de bir” […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[33],"tags":[],"yoast_head":"\n
Down Sendromu Tarama Testi Sonu\u00e7lar\u0131 - \u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Down Sendromu Tarama Testi Sonu\u00e7lar\u0131 - \u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi\" \/>\n<meta property=\"og:description\" content=\"Bir tarama testi bana hangi bilgileri verir? Say\u0131 b\u00fcy\u00fcd\u00fck\u00e7e risk azal\u0131r. T\u00fcm tarama testi sonu\u00e7lar\u0131 “…’de bir” (\u00f6rn. “100’de bir” veya “1500’de bir”) \u015feklinde verilir. Ayn\u0131 sonu\u00e7lar, y\u00fczdelik de\u011ferler olarak da verilebilir. Bu say\u0131lar, bebekte Down sendromu bulunma olas\u0131l\u0131\u011f\u0131n\u0131 g\u00f6sterir. \u00d6rne\u011fin, “100’de bir” sonucu, bebe\u011fin 100’de bir olas\u0131l\u0131kla Down sendromlu olaca\u011f\u0131 anlam\u0131na gelmektedir. “1500’de bir” […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/\" \/>\n<meta property=\"og:site_name\" content=\"\u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi\" \/>\n<meta property=\"article:publisher\" content=\"http:\/\/facebook.com\/op.dr.hakankilavuz\" \/>\n<meta property=\"article:published_time\" content=\"2013-02-16T20:47:16+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/izmirkarsiyakakadindogummerkezi.com\/wp-content\/uploads\/2013\/02\/karar.jpg\" \/>\n<meta name=\"author\" content=\"hakan\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@opdrkilavuz\" \/>\n<meta name=\"twitter:site\" content=\"@opdrkilavuz\" \/>\n<meta name=\"twitter:label1\" content=\"Yazan:\" \/>\n\t<meta name=\"twitter:data1\" content=\"hakan\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tahmini okuma s\u00fcresi\" \/>\n\t<meta name=\"twitter:data2\" content=\"8 dakika\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/\",\"url\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/\",\"name\":\"Down Sendromu Tarama Testi Sonu\u00e7lar\u0131 - \u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi\",\"isPartOf\":{\"@id\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/#website\"},\"datePublished\":\"2013-02-16T20:47:16+00:00\",\"dateModified\":\"2013-02-16T20:47:16+00:00\",\"author\":{\"@id\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/#\/schema\/person\/8a752617726b9b02bd10a28c1c4509a4\"},\"breadcrumb\":{\"@id\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/#breadcrumb\"},\"inLanguage\":\"tr\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Ana sayfa\",\"item\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Down Sendromu Tarama Testi Sonu\u00e7lar\u0131\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/#website\",\"url\":\"https:\/\/izmirkarsiyakakadindogummerkezi.com\/\",\"name\":\"\u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi\",\"description\":\"Op. 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Say\u0131 b\u00fcy\u00fcd\u00fck\u00e7e risk azal\u0131r. T\u00fcm tarama testi sonu\u00e7lar\u0131 “…’de bir” (\u00f6rn. “100’de bir” veya “1500’de bir”) \u015feklinde verilir. Ayn\u0131 sonu\u00e7lar, y\u00fczdelik de\u011ferler olarak da verilebilir. Bu say\u0131lar, bebekte Down sendromu bulunma olas\u0131l\u0131\u011f\u0131n\u0131 g\u00f6sterir. \u00d6rne\u011fin, “100’de bir” sonucu, bebe\u011fin 100’de bir olas\u0131l\u0131kla Down sendromlu olaca\u011f\u0131 anlam\u0131na gelmektedir. “1500’de bir” […]","og_url":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/","og_site_name":"\u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi","article_publisher":"http:\/\/facebook.com\/op.dr.hakankilavuz","article_published_time":"2013-02-16T20:47:16+00:00","og_image":[{"url":"http:\/\/izmirkarsiyakakadindogummerkezi.com\/wp-content\/uploads\/2013\/02\/karar.jpg"}],"author":"hakan","twitter_card":"summary_large_image","twitter_creator":"@opdrkilavuz","twitter_site":"@opdrkilavuz","twitter_misc":{"Yazan:":"hakan","Tahmini okuma s\u00fcresi":"8 dakika"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/","url":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/","name":"Down Sendromu Tarama Testi Sonu\u00e7lar\u0131 - \u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi","isPartOf":{"@id":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/#website"},"datePublished":"2013-02-16T20:47:16+00:00","dateModified":"2013-02-16T20:47:16+00:00","author":{"@id":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/#\/schema\/person\/8a752617726b9b02bd10a28c1c4509a4"},"breadcrumb":{"@id":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/#breadcrumb"},"inLanguage":"tr","potentialAction":[{"@type":"ReadAction","target":["https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/down-sendromu-tarama-testi-sonuclari\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Ana sayfa","item":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/"},{"@type":"ListItem","position":2,"name":"Down Sendromu Tarama Testi Sonu\u00e7lar\u0131"}]},{"@type":"WebSite","@id":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/#website","url":"https:\/\/izmirkarsiyakakadindogummerkezi.com\/","name":"\u0130zmir Kar\u015f\u0131yaka Kad\u0131n Do\u011fum Merkezi","description":"Op. 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Bir tarama testi bana hangi bilgileri verir? Say\u0131 b\u00fcy\u00fcd\u00fck\u00e7e risk azal\u0131r. T\u00fcm tarama testi sonu\u00e7lar\u0131 “…’de bir” (\u00f6rn. “100’de bir” veya “1500’de bir”) \u015feklinde verilir. Ayn\u0131 sonu\u00e7lar, y\u00fczdelik de\u011ferler olarak da verilebilir. Bu say\u0131lar, bebekte Down sendromu bulunma olas\u0131l\u0131\u011f\u0131n\u0131 g\u00f6sterir. \u00d6rne\u011fin, “100’de bir” sonucu, bebe\u011fin 100’de bir olas\u0131l\u0131kla Down sendromlu olaca\u011f\u0131 anlam\u0131na gelmektedir. “1500’de bir” […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[33],"tags":[],"yoast_head":"\n